The effect of head and neck irradiation on taste dysfunction: a prospective study.

摘要: Taste loss is a major cause of morbidity in patients undergoing head and neck irradiation. In prospective study, 26 radical irradiation at the Royal Marsden Hospital, Sutton, Queen Elizabeth Birmingham, were assessed for taste xerostomia. was tested using subjective questionnaire by objective testing with series solute solutions (sucrose, sodium chloride, urea hydrochloric acid) increasing concentrations, to determine threshold level sensation, both before after radiotherapy. Xerostomia patient questionnaire. The volume tongue parotid contained within high dose radiation treatment field determined each correlated degree as well results have shown that (r = 0.59; P 0.0016) 0.78; 0.0001) significantly associated proportion tongue, but not parotid, field. data gave no evidence suggest any relationship between recovery or irradiated. However, loss, 1 month completing radiotherapy seen two patients, whom had been treated wedge pair technique avoid contralateral area tongue. Changes xerostomia proportions 0.54; 0.004) 0.82; fields.(ABSTRACT TRUNCATED AT 250 WORDS)