The Genetic Basis of Cancer
作者： Akseli Hemminki , Kari Hemminki
DOI: 10.1007/978-1-59259-785-7_2
关键词:
摘要: Cancer is a genetic disease in which malignant cells have undergone mutations and epigenetic changes but maintain the transformed phenotype even when cultured or injected into immunologically tolerant experimental animals (1,2). However, most of events tumors are somatic (i.e., not hereditary), brought about environmentally randomly, identified inherited (often referred to as “genetic”) causes account for small proportion all cancers.
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