Magnesium Intake Is Inversely Associated With Coronary Artery Calcification

摘要: Objectives The aim of this study was to examine whether magnesium intake is associated with coronary artery calcification (CAC) and abdominal aortic (AAC). Background Animal cell studies suggest that may prevent within atherosclerotic plaques underlying cardiovascular disease. Little known about the association in humans. Methods We examined cross-sectional associations self-reported total (dietary supplemental) estimated by food frequency questionnaire CAC AAC participants Framingham Heart Study who were free disease underwent Multi-Detector Computed Tomography (MDCT) heart abdomen (n = 2,695; age: 53 ± 11 years), using multivariate-adjusted Tobit regression. quantified modified Agatston scores (AS). Models adjusted for age, sex, body mass index, smoking status, systolic blood pressure, fasting insulin, total-to-high-density lipoprotein cholesterol ratio, use hormone replacement therapy (women only), menopausal status treatment hyperlipidemia, hypertension, prevention, or diabetes, as well calcium, vitamins D K, saturated fat, fiber, alcohol, energy. Secondary analyses included logistic regressions outcomes cut-points (AS >0 AS ≥90th percentile age sex), sex-stratified analyses. Results In fully models, a 50-mg/day increment 22% lower (p Conclusions community-dwelling disease, inversely arterial calcification, which play contributing role magnesium's protective stroke fatal