An overview of the issues: physiological effects of bed rest and restricted physical activity

摘要: Reduction of exercise capacity with confinement to bed rest is well recognized. Underlying physiological mechanisms include dramatic reductions in maximal stroke volume, cardiac output, and oxygen uptake. However, by itself does not appear contribute dysfunction. Increased muscle fatigue associated reduced blood flow, red cell capillarization oxidative enzymes. Loss mass bone density may be reflected strength higher risk for injury bones joints. The resultant deconditioning caused can independent the primary disease physically debilitating patients who attempt reambulate normal active living working. A challenge clinicians health care specialists has been identification appropriate effective methods restore physical during or after restricted activity prolonged rest. examination responses training healthy subjects provided significant information develop rehabilitation treatments. successful application acute enhance orthostatic stability, daily endurance maintain aerobic capacity, specific resistance exercises musculoskeletal integrity rather than use surgical, pharmacological, other medical treatments clinical conditions enhanced investigation understanding underlying that distinguish from disease. This symposium presents an overview cardiovascular work following regimens have proven ameliorating reversing these adverse effects.