Immune aspects of embryo-maternal cross-talk in the bovine uterus.

摘要: This mini-review summarizes the results of recent transcriptome studies bovine endometrium during estrous cycle and pre-implantation phase, with a focus on immune response genes. Gene expression changes in were compared to similar study equine endometrium. The indicate species-specific patterns, particularly for genes functions. These are presumably consequence adaptations differences physiology reproduction each species, including development conceptus, hormone profiles cycle, insemination. from number as well comparison effects human interferon alpha endometrial gene expression, suggest that pregnancy there is no general suppression maternal system, but rather fine-tuned regulation cells. facilitates tolerance immunologically ‘foreign’ conceptus at same time activation system defend against microbial viral infections. Furthermore, differentially expressed samples reveals changes, indicating existence shared mechanisms preparation embryo implantation.