作者: Ashwin S. Dharmadhikari , Matsie Mphahlele , Anton Stoltz , Kobus Venter , Rirhandzu Mathebula
DOI: 10.1164/RCCM.201107-1190OC
关键词:
摘要: Rationale: Drug-resistant tuberculosis transmission in hospitals threatens staff and patient health. Surgical face masks used by patients with (TB) are believed to reduce but have not been rigorously tested.Objectives: We sought quantify the efficacy of surgical when worn multidrug-resistant TB (MDR-TB).Methods: Over 3 months, 17 pulmonary MDR-TB occupied an ward South Africa wore on alternate days. Ward air was exhausted two identical chambers, each housing 90 pathogen-free guinea pigs that breathed either (intervention group) or did wear (control group). Efficacy based differences pig infections chamber.Measurements Main Results: Sixty-nine control (76.6%; 95% confidence interval [CI], 68–85%) became infected, compared 36 intervention (40%; CI, 31–51%), represent...