Madr2 tumour suppressor gene

作者: Liliana Attisano , W. Stephen Scherer , Jeffrey Wrana

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摘要: A new human gene, MADR2, has been cloned and sequenced, identified as a tumour suppressor gene. The protein encoded by the shown to participate in TGFβ signalling pathway be phosphorylated on stimulation of receptor.

参考文章(12)
Radaelli Luigi, AUTOMATIC CAR PARK ,(1997)
Kenneth O. Devaney, Thomas E. Carey, Kenneth D. McClatchey, Christopher J. Frank, Evidence That Loss of Chromosome 18q Is Associated with Tumor Progression Cancer Research. ,vol. 57, pp. 824- 827 ,(1997)
Tetsuya Mitsudomi, Masaaki Nagatake, Kosaku Uchida, Masashi Kondo, Akira Masuda, Yasushi Yatabe, Toshitada Takahashi, Hirotaka Osada, Takashi Takahashi, Somatic in Vivo Alterations of the DPC4 Gene at 18q21 in Human Lung Cancers Cancer Research. ,vol. 56, pp. 2718- 2720 ,(1996)
D J Weatherall, Scope and limitations of gene therapy British Medical Bulletin. ,vol. 51, pp. 1- 11 ,(1995) , 10.1093/OXFORDJOURNALS.BMB.A072939
Gregory J. Riggins, Sam Thiagalingam, Ester Rozenblum, Craig L. Weinstein, Scott E. Kern, Stanley R. Hamilton, James K.V. Willson, Sanford D. Markowitz, Kenneth W. Kinzler, Bert Vogelstein, Mad-related genes in the human Nature Genetics. ,vol. 13, pp. 347- 349 ,(1997) , 10.1038/NG0796-347
J C Baker, R M Harland, A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. Genes & Development. ,vol. 10, pp. 1880- 1889 ,(1996) , 10.1101/GAD.10.15.1880
Fang Liu, Akiko Hata, Julie C. Baker, Jacqueline Doody, Juan Cárcamo, Richard M. Harland, Joan Massagué, A human Mad protein acting as a BMP-regulated transcriptional activator Nature. ,vol. 381, pp. 620- 623 ,(1996) , 10.1038/381620A0
Jonathan M Graff, Anu Bansal, Douglas A Melton, Xenopus mad proteins transduce distinct subsets of signals for the TGFβ superfamily Cell. ,vol. 85, pp. 479- 487 ,(1996) , 10.1016/S0092-8674(00)81249-0
Pamela A Hoodless, Theo Haerry, Shirin Abdollah, Mark Stapleton, Michael B O'Connor, Liliana Attisano, Jeffrey L Wrana, None, MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways Cell. ,vol. 85, pp. 489- 500 ,(1996) , 10.1016/S0092-8674(00)81250-7
Laurel A. Raftery, Elena H. Chartoff, William M. Gelbart, Jeff J. Sekelsky, Stuart J. Newfeld, Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics. ,vol. 139, pp. 1347- 1358 ,(1995) , 10.1093/GENETICS/139.3.1347