摘要: Purpose of review The purpose this is to summarize recent advances in our understanding the impact sleep disturbances have on health, with particular focus brain. present considers influence disturbance neurovascular unit; role neurodegenerative diseases; and relevant strategies neuro-immuno-endocrine interactions that likely contribute restorative power sleep. Given latest discoveries about brain's waste clearance system its relationship diseases like Alzheimer's disease, gives a brief overview molecular mechanisms behind loss-related impairments. Recent findings evidence indicates plays vital homeostasis. Sleep loss has been linked elevated risks for cognitive mood disorders, underscored by impaired synaptic transmission. glymphatic shown be modulated implicated disorders. Summary Interactions between quality, immune system, disease are complex challenge distil. These frequently bidirectional, because sleep's characterization as an early symptom potential factor contributing development progression VIDEO ABSTRACT.
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