Microbes: possible link between modern lifestyle transition and the rise of metabolic syndrome
作者： S. Moossavi , F. Bishehsari
DOI: 10.1111/OBR.12784
关键词:
摘要: The rapid decrease in infectious diseases globally has coincided with an increase the prevalence of obesity and other components metabolic syndrome. Insulin resistance is a common feature syndrome can be influenced by genetic non-genetic/environmental factors. emergence epidemics over only few decades suggests more prominent role latter. Changes our environment lifestyle have indeed paralleled rise Gastrointestinal tract microbiota, composition which plays significant host physiology, including metabolism energy homeostasis, are distinctly different within context Among humans, recent lifestyle-related changes could linked to diversity 'ancient' microbiota. Given co-adaptation co-evolution microbiota immune system long period time, it plausible that such trigger aberrant responses, thereby predisposing individual variety diseases. Here, we review current evidence supporting for gut ongoing We conclude population-level shifts play mediatory between factors pathogenesis insulin
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