Identification of ALK as a major familial neuroblastoma predisposition gene

作者: Yaël P Mossé , Marci Laudenslager , Luca Longo , Kristina A Cole , Andrew Wood

DOI: 10.1038/NATURE07261

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摘要: Neuroblastoma is a childhood cancer that can be inherited, but the genetic aetiology is largely unknown. Here we show that germline mutations in the anaplastic lymphoma kinase (ALK…

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