A Prospective Population-Based Study of Menopausal Symptoms
作者： Lorraine Dennerstein , Emma C Dudley , John L Hopper , Janet R Guthrie , Henry G Burger
DOI: 10.1016/S0029-7844(00)00930-3
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摘要: Abstract Objective: To identify symptoms that change in prevalence and severity during midlife evaluate their relationships to menopausal status, hormonal levels, other factors. Methods: In a longitudinal, population-based study of 438 Australian-born women observed for 7 years with an 89% retention rate, 172 advanced from premenopause perimenopause or postmenopause. Annual measures included 33-item symptom check list; psychosocial, lifestyle, health-related factors; menstrual status; hormone usage; blood levels follicle-stimulating estradiol (E2). Results: Increasing early late were the number who reported five more (+14%), hot flushes (+27%), night sweats (+17%) vaginal dryness (all P Conclusion: Although middle-aged are highly symptomatic, appear be specifically related changes transition vasomotor symptoms, dryness, breast tenderness. Insomnia reflected bothersome psychosocial
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