NAD glycohydrolase activity in the liver of rats fed on excess leucine diet and low or high protein diet.

作者: Hideno KUBOTA , Kenji NOMURA , Osamu YAMADA , Mariko SHIN , Kejij SANO

DOI: 10.3177/JNSV.28.57

关键词:

摘要: In rats fed for 2 weeks on a 10% casein diet suaolemented with 5% leucine, the hepatic NAD content was lowered when comparing control pair-fed diet. The glycohydrolase [EC 3.2.2.5] activity increased by 25% in leucine-supplemented diet-fed and 40% nicotinic acid-free rats. non-protein freely 1 week elevated 60% compared to 18% former animals significantly lower than that latter. 70% caused changes neither nor activity. These results indicated an inverse relationship between

参考文章(22)
Sidney P. Colowick, Nathan O. Kaplan, Margaret M. Ciotti, The reaction of pyridine nucleotide with cyanide and its analytical use. Journal of Biological Chemistry. ,vol. 191, pp. 447- 459 ,(1951) , 10.1016/S0021-9258(18)55950-0
Hiroshi Okamoto, Fumiko Okada, Osamu Hayaishi, Kynurenine Metabolism in Hyperthyroidism A BIOCHEMICAL BASIS FOR THE LOW NAD(P) LEVEL IN HYPERTHYROID RAT LIVER Journal of Biological Chemistry. ,vol. 246, pp. 7759- 7763 ,(1971) , 10.1016/S0021-9258(19)45840-7
K.W. Bock, P. Siekevitz, G.E. Palade, Localization and Turnover Studies of Membrane Nicotinamide Adenine Dinucleotide Glycohydrolase in Rat Liver Journal of Biological Chemistry. ,vol. 246, pp. 188- 195 ,(1971) , 10.1016/S0021-9258(18)62548-7
D. Mark Hegsted, R.C. Mills, C.A. Elvehjem, E.B. Hart, CHOLINE IN THE NUTRITION OF CHICKS Journal of Biological Chemistry. ,vol. 138, pp. 459- 466 ,(1941) , 10.1016/S0021-9258(18)51369-7
Q. R. Rogers, R. I. Tannous, A. E. Harper, Effects of excess leucine on growth and food selection. Journal of Nutrition. ,vol. 91, pp. 561- 572 ,(1967) , 10.1093/JN/91.4.561
N. Raghuramulu, B. S. Narasinga Rao, C. Gopalan, Amino Acid Imbalance and Tryptophanniacin Metabolism The Journal of Nutrition. ,vol. 86, pp. 100- 106 ,(1965) , 10.1093/JN/86.1.100
K Ueda, M Fukushima, H Okayama, O Hayaishi, Nicotinamide adenine dinucleotide glycohydrolase from rat liver nuclei. Isolation and characterization of a new enzyme. Journal of Biological Chemistry. ,vol. 250, pp. 7541- 7546 ,(1975) , 10.1016/S0021-9258(19)40852-1
CHRISTIAN STREFFER, The biosynthesis of NAD in the liver of irradiated mice. The Journal of vitaminology. ,vol. 14, pp. 130- 134 ,(1968) , 10.5925/JNSV1954.14.SUPPLEMENT_130