Lovastatin vs Cholestyramine Therapy for Primary Hypercholesterolemia

摘要: To the Editor.— Lovastatin is a remarkable drug. Better than any other medication yet available, lovastatin promptly lowers low-density lipoprotein cholesterol levels, with few apparent side effects. When I and my internist colleagues in west central Maine began prescribing October 1987, we were struck soon by what seemed like an unusual incidence of chest pain patients recently started on therapy In November 1987 one 18 December seven 20 admissions to Franklin Memorial Hospital for involved taking lovastatin. three cases (two individual patients), starting did not seem have changed previous tempo coronary symptoms. However, five severe atherosclerosis experienced distinct acceleration symptoms between 49 days after therapy; four developed newly unstable angina suffered acute myocardial infarction. Was this