Crystal structure of 4-{[(1H-1,2,4-triazol-1-yl)meth-yl]sulfan-yl}phenol.
作者： Yong-Le Zhang , Chuang Zhang , Wei Guo , Jing Wang
DOI: 10.1107/S1600536814019965
关键词:
摘要: In the title compound, C9H9N3OS, plane of benzene ring forms a dihedral angle 33.40 (5)° with that triazole group. crystal, molecules are linked by O—H⋯N hydrogen bonds involving phenol –OH group and one unsubstituted N atoms ring, resulting in chains along [010]. These further extended into layer parallel to (001) weak C—H⋯N hydrogen-bond interactions. Aromatic π–π stacking [centroid–centroid separation = 3.556 (1) A] between rings links layers three-dimensional network.
sci-hub.se 参考文章(8)
Byran Gowramma, Selvaraj Jubie, Kannan Elango, Rajagopal Kalirajan, Subramanian Gomathy, Shanish Antony, Pranabesh Sikdar, SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME SCHIFF BASES OF (4-(AMINO) -5- PHENYL- 4H-1, 2, 4-TRIAZOLE- 3- THIOL) Pakistan Journal of Pharmaceutical Sciences. ,vol. 24, pp. 109- 112 ,(2011)
Imtiaz Khan, Sajid Ali, Shahid Hameed, Nasim Hasan Rama, Muhammad Tahir Hussain, Abdul Wadood, Reaz Uddin, Zaheer Ul-Haq, Ajmal Khan, Sajjad Ali, M. Iqbal Choudhary, Synthesis, antioxidant activities and urease inhibition of some new 1,2,4-triazole and 1,3,4-thiadiazole derivatives. European Journal of Medicinal Chemistry. ,vol. 45, pp. 5200- 5207 ,(2010) , 10.1016/J.EJMECH.2010.08.034
Navin B Patel, Imran H Khan, Christophe Pannecouque, Erik De Clercq, None, Anti-HIV, antimycobacterial and antimicrobial studies of newly synthesized 1,2,4-triazole clubbed benzothiazoles Medicinal Chemistry Research. ,vol. 22, pp. 1320- 1329 ,(2013) , 10.1007/S00044-012-0129-4
R. W. Sidwell, J. H. Huffman, G. P. Khare, Lois, B. Allen, J. T. Witkowski, Roland, K. Robins, Broad-Spectrum Antiviral Activity of Virazole: 1-f8- D-Ribofuranosyl- 1,2,4-triazole- 3-carboxamide Science. ,vol. 177, pp. 705- 706 ,(1972) , 10.1126/SCIENCE.177.4050.705
Umut Salgın-Gökşen, Nesrin Gökhan-Kelekçi, Özgür Göktaş, Yavuz Köysal, Ekrem Kılıç, Şamil Işık, Göknur Aktay, Meral Özalp, 1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities. Bioorganic & Medicinal Chemistry. ,vol. 15, pp. 5738- 5751 ,(2007) , 10.1016/J.BMC.2007.06.006
Ronghui Lin, Peter J. Connolly, Shenlin Huang, Steven K. Wetter, Yanhua Lu, William V. Murray, Stuart L. Emanuel, Robert H. Gruninger, Angel R. Fuentes-Pesquera, Catherine A. Rugg, Steven A. Middleton, Linda K. Jolliffe, 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors: Synthesis and Evaluation of Biological Activities Journal of Medicinal Chemistry. ,vol. 48, pp. 4208- 4211 ,(2005) , 10.1021/JM050267E
Jianming Xu, Yongbing Cao, Jun Zhang, Shichong Yu, Yan Zou, Xiaoyun Chai, Qiuye Wu, Dazhi Zhang, Yuanying Jiang, Qingyan Sun, Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives. European Journal of Medicinal Chemistry. ,vol. 46, pp. 3142- 3148 ,(2011) , 10.1016/J.EJMECH.2011.02.042
George M. Sheldrick, A short history of SHELX Acta Crystallographica Section A. ,vol. 64, pp. 112- 122 ,(2008) , 10.1107/S0108767307043930