Preparation of block-brush PEG-b-P(NIPAM-g-DMAEMA) and its dual stimulus-response
作者： Bo-Yu Zhang , Wei-Dong He , Wen-Tao Li , Li-Ying Li , Ke-Ren Zhang
DOI: 10.1016/J.POLYMER.2010.05.012
关键词:
摘要: Abstract Well-defined dually responsive block-brush copolymer of poly(ethylene glycol)-b-[poly(N-isopropylacrylamide)-g-poly(N,N-dimethylamino-ethylmethacrylate)], [PEG-b-P(NIPAM-g-PDMAEMA)] was successfully prepared by the combination atom transfer radical polymerization (ATRP) and click chemistry based on azide-capped PDMAEMA alkyne-pending PEG-b-PNIPAM copolymer. Azide-capped synthesized through ATRP DMAEMA monomer using an azide-functionalized initiator β-azidoethyl-2-bromoisobutyrate. Alkyne-pending obtained copolymerization NIPAM with propargyl acrylate. The final reaction between these two polymer precursors. Because characteristics three different blocks, exhibited thermo- pH-responsive behavior. behaviors were studied laser light scattering, temperature-dependent turbidity measurement micro differential scanning calorimetry. phase transition temperature increased decrease pH value. At pH = 5.0, displayed weak thermo-responsive behavior might form uni-molecular micelles upon heating. higher values, aggregated intermolecularly into during transition.
elsevier.com
sci-hub.se 参考文章(50)
Ye-Zi You, Qing-Hui Zhou, Devika Soundara Manickam, Lei Wan, Guang-Zhao Mao, David Oupický, Dually responsive multiblock copolymers via reversible addition- fragmentation chain transfer polymerization: Synthesis of temperature- and redox-responsive copolymers of poly(N-isopropylacrylamide) and poly(2-(dimethylamino)ethyl methacrylate) Macromolecules. ,vol. 40, pp. 8617- 8624 ,(2007) , 10.1021/MA071176P
Giancarlo Masci, Laura Giacomelli, Vittorio Crescenzi, Atom Transfer Radical Polymerization of N-Isopropylacrylamide Macromolecular Rapid Communications. ,vol. 25, pp. 559- 564 ,(2004) , 10.1002/MARC.200300140
Christian W. Tornøe, Caspar Christensen, Morten Meldal, Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides. Journal of Organic Chemistry. ,vol. 67, pp. 3057- 3064 ,(2002) , 10.1021/JO011148J
Maria Ruela Talingting, Petr Munk, S. E. Webber, Zdenek Tuzar, Onion-Type Micelles from Polystyrene-block-poly(2-vinylpyridine) and Poly(2-vinylpyridine)-block-poly(ethylene oxide) Macromolecules. ,vol. 32, pp. 1593- 1601 ,(1999) , 10.1021/MA981269U
Hosei Shinoda, Krzysztof Matyjaszewski, Structural Control of Poly(Methyl Methacrylate)-g-poly(Lactic Acid) Graft Copolymers by Atom Transfer Radical Polymerization (ATRP) Macromolecules. ,vol. 34, pp. 6243- 6248 ,(2001) , 10.1021/MA0105791
Jian Li, Wei-Dong He, Shou-chen Han, Xiao-li Sun, Li-ying Li, Bo-yu Zhang, Synthesis and micellization of PSt‐PNIPAM‐PDMAEMA hetero‐arm star polymer with double thermo‐responsibility Journal of Polymer Science Part A. ,vol. 47, pp. 786- 796 ,(2009) , 10.1002/POLA.23195
Xulin Jiang, Martin C. Lok, Wim E. Hennink, Degradable-brushed pHEMA-pDMAEMA synthesized via ATRP and click chemistry for gene delivery. Bioconjugate Chemistry. ,vol. 18, pp. 2077- 2084 ,(2007) , 10.1021/BC0701186
Julien Bernard, Arnaud Favier, Thomas P Davis, Christopher Barner-Kowollik, Martina H Stenzel, None, Synthesis of poly(vinyl alcohol) combs via MADIX/RAFT polymerization Polymer. ,vol. 47, pp. 1073- 1080 ,(2006) , 10.1016/J.POLYMER.2005.12.004
Jingquan Liu, Lei Tao, Jiangtao Xu, Zhongfan Jia, Cyrille Boyer, Thomas P. Davis, RAFT controlled synthesis of six-armed biodegradable star polymeric architectures via a ‘core-first’ methodology Polymer. ,vol. 50, pp. 4455- 4463 ,(2009) , 10.1016/J.POLYMER.2009.07.018
Youyong Xu, Sreenath Bolisetty, Markus Drechsler, Bing Fang, Jiayin Yuan, Matthias Ballauff, Axel H.E. Müller, pH and salt responsive poly(N,N-dimethylaminoethyl methacrylate) cylindrical brushes and their quaternized derivatives Polymer. ,vol. 49, pp. 3957- 3964 ,(2008) , 10.1016/J.POLYMER.2008.06.051