Precision medicine: beyond genomics to targeted therapies.

Alan Saghatelian, Gary J. Patti, Nicola Zamboni, Defining the metabolome: size, flux, and regulation. Molecular Cell. ,vol. 58, pp. 699- 706 ,(2015) , 10.1016/J.MOLCEL.2015.04.021

Aleksandra A. Kolodziejczyk, Jong Kyoung Kim, Valentine Svensson, John C. Marioni, Sarah A. Teichmann, The technology and biology of single-cell RNA sequencing. Molecular Cell. ,vol. 58, pp. 610- 620 ,(2015) , 10.1016/J.MOLCEL.2015.04.005

Michael B. Brenner, Soumya Raychaudhuri, Joerg Ermann, Deepak A. Rao, Nikola C. Teslovich, Immune cell profiling to guide therapeutic decisions in rheumatic diseases Nature Reviews Rheumatology. ,vol. 11, pp. 541- 551 ,(2015) , 10.1038/NRRHEUM.2015.71

Rachael E. Hawtin, Alessandra Cesano, Immune monitoring technology primer: Single Cell Network Profiling (SCNP). Journal for ImmunoTherapy of Cancer. ,vol. 3, pp. 34- 34 ,(2015) , 10.1186/S40425-015-0075-Z

Feriyl Bhaijee, Thomas Huebner, Ralph H. Hruban, Laura D. Wood, Nathan Cuka, Drew M. Pardoll, Nickolas Papadopoulos, Kenneth W. Kinzler, Shibin Zhou, Toby C. Cornish, Janis M. Taube, Robert A. Anders, James R. Eshleman, Bert Vogelstein, Luis A. Diaz, Dung T. Le, Jennifer N. Uram, Hao Wang, Bjarne R. Bartlett, Holly Kemberling, Aleksandra D. Eyring, Andrew D. Skora, Brandon S. Luber, Nilofer S. Azad, Dan Laheru, Barbara Biedrzycki, Ross C. Donehower, Atif Zaheer, George A. Fisher, Todd S. Crocenzi, James J. Lee, Steven M. Duffy, Richard M. Goldberg, Albert de la Chapelle, Minori Koshiji, PD-1 Blockade in Tumors with Mismatch-Repair Deficiency The New England Journal of Medicine. ,vol. 372, pp. 2509- 2520 ,(2015) , 10.1056/NEJMOA1500596

George Georgiou, Gregory C Ippolito, John Beausang, Christian E Busse, Hedda Wardemann, Stephen R Quake, The promise and challenge of high-throughput sequencing of the antibody repertoire. Nature Biotechnology. ,vol. 32, pp. 158- 168 ,(2014) , 10.1038/NBT.2782

Peter W. Hamilton, Peter Bankhead, Yinhai Wang, Ryan Hutchinson, Declan Kieran, Darragh G. McArt, Jacqueline James, Manuel Salto-Tellez, Digital pathology and image analysis in tissue biomarker research. Methods. ,vol. 70, pp. 59- 73 ,(2014) , 10.1016/J.YMETH.2014.06.015

Kelvin Sze-Yin Leung, Bonnie Mei-Wah Fong, LC–MS/MS in the routine clinical laboratory: has its time come? Analytical and Bioanalytical Chemistry. ,vol. 406, pp. 2289- 2301 ,(2014) , 10.1007/S00216-013-7542-5

Jaideep S Dudani, Harsha Kittur, Rajan P Kulkarni, Dino Di Carlo, Westbrook M Weaver, Peter Tseng, Anja Kunze, Mahdokht Masaeli, Aram J Chung, Advances in high-throughput single-cell microtechnologies. Current Opinion in Biotechnology. ,vol. 25, pp. 114- 123 ,(2014) , 10.1016/J.COPBIO.2013.09.005

Timour Baslan, James Hicks, Single cell sequencing approaches for complex biological systems Current Opinion in Genetics & Development. ,vol. 26, pp. 59- 65 ,(2014) , 10.1016/J.GDE.2014.06.004