Double-layered composite particles as a complex stationary phase for high-performance liquid chromatography
作者： Futaba Honda , Hirotaka Honda , Masumi Koishi , Takashi Matsuno
DOI: 10.1016/S0021-9673(97)00226-4
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摘要: A composite particle with a double-coating layer consisting of silica (0.3 μm), titania (0.017 μm) and polyethylene beads (13.1 was prepared by dry impact blending method. The employed as complex stationary phase for high-performance liquid chromatography. Forming the surface double caused change in acidity oxides; result, enhanced chromatographic retention behavior depending on ionic interaction. Therefore, demonstrates properties novel rather than those mixture two phases. By using multiple mechanisms, separation some basic drugs simultaneous analysis acids bases were performed.
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