APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men.
作者： Gie Ken-Dror , Philippa J. Talmud , Steve E. Humphries , Fotios Drenos
DOI: 10.2119/MOLMED.2010.00044
关键词:
摘要: … is little data for other SNPs in the APOE/C1/C4/C2 gene cluster or for the gene cluster haplotypes. The APOE ε2 allele and the APOC2 SNP rs5127 were both independently associated …
biomedcentral.com
springer.com
bristol.ac.uk
sci-hub.se 参考文章(51)
E. Sehayek, S. Eisenberg, Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway. Journal of Biological Chemistry. ,vol. 266, pp. 18259- 18267 ,(1991) , 10.1016/S0021-9258(18)55263-7
K H Weisgraber, R W Mahley, R C Kowal, J Herz, J L Goldstein, M S Brown, Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein. Journal of Biological Chemistry. ,vol. 265, pp. 22453- 22459 ,(1990) , 10.1016/S0021-9258(18)45726-2
Robert R Graham, Carl D Langefeld, Patrick M Gaffney, Ward A Ortmann, Scott A Selby, Emily C Baechler, Katherine B Shark, Theresa C Ockenden, Kristine E Rohlf, Kathleen L Moser, William M Brown, Sherine E Gabriel, Ronald P Messner, Richard A King, Pavel Horak, James T Elder, Philip E Stuart, Steven S Rich, Timothy W Behrens, Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus Arthritis Research. ,vol. 3, pp. 299- 305 ,(2001) , 10.1186/AR319
G Siest, T Pillot, A Régis-Bailly, B Leininger-Muller, J Steinmetz, M M Galteau, S Visvikis, Apolipoprotein E: an important gene and protein to follow in laboratory medicine. Clinical Chemistry. ,vol. 41, pp. 1068- 1086 ,(1995) , 10.1093/CLINCHEM/41.8.1068
Xiao-he Chen, Santiago Rodríguez, Emma Hawe, Philippa J. Talmud, George J. Miller, Peter Underhill, Stephen E. Humphries, Ian N.M. Day, Evidence of admixture from haplotyping in an epidemiological study of UK Caucasian males: implications for association analyses. Human Heredity. ,vol. 57, pp. 142- 155 ,(2004) , 10.1159/000079245
Marı́a J Artiga, Marı́a J Bullido, Isabel Sastre, Marı́a Recuero, Miguel A Garcı́a, Jesús Aldudo, Jesús Vázquez, Fernando Valdivieso, Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene. FEBS Letters. ,vol. 421, pp. 105- 108 ,(1998) , 10.1016/S0014-5793(97)01543-3
Jonathan Marchini, David Cutler, Nick Patterson, Matthew Stephens, Eleazar Eskin, Eran Halperin, Shin Lin, Zhaohui S Qin, Heather M Munro, Gonçalo R Abecasis, Peter Donnelly, None, A Comparison of Phasing Algorithms for Trios and Unrelated Individuals The American Journal of Human Genetics. ,vol. 78, pp. 437- 450 ,(2006) , 10.1086/500808
William P. Castelli, Keaven Anderson, Peter W.F. Wilson, Daniel Levy, Lipids and risk of coronary heart disease The Framingham Study Annals of Epidemiology. ,vol. 2, pp. 23- 28 ,(1992) , 10.1016/1047-2797(92)90033-M
Kenneth J. Rothman, No adjustments are needed for multiple comparisons. Epidemiology. ,vol. 1, pp. 43- 46 ,(1990) , 10.1097/00001648-199001000-00010
Jacqueline A. Cooper, George J. Miller, Kenneth A. Bauer, James H. Morrissey, Thomas W. Meade, David J. Howarth, Samad Barzegar, Jacqueline P. Mitchell, Robert D. Rosenberg, Comparison of Novel Hemostatic Factors and Conventional Risk Factors for Prediction of Coronary Heart Disease Circulation. ,vol. 102, pp. 2816- 2822 ,(2000) , 10.1161/01.CIR.102.23.2816