PATIENT-SPECIFIC DOSIMETRY FOR PEDIATRIC IMAGING OF 99mTc-DIMERCAPTOSUCCINIC ACID WITH GATE MONTE CARLO CODE.

摘要: In this study, radiation absorbed dose of 99mTc-dimercaptosuccinic acid (DMSA) in critical organs was calculated using Monte Carlo simulation. Ten child patients with genitourinary abnormalities were imaged a series planar, SPECT and MRI, after injection 99mTc-DMSA. Patient-specific organ segmentation performed on MRI used as input GATE. Organs substantial uptake included kidneys, bladder liver. The mean coefficients (mGy/MBq) 0.063, 0.058, 0.018, 0.016, 0.013 0.010 for the right kidney, left bones, urinary wall, liver gonads, respectively. remainder body 0.012 mGy/MBq. authors implemented an image-based method patient-specific 3D calculation. This study also demonstrates possibility to obtain attenuation map from be simulations transport energy deposition phantom methods.