Overt diabetes mellitus among newly diagnosed Ugandan tuberculosis patients: a cross sectional study

摘要: There is a documented increase of diabetes mellitus in Sub Saharan Africa, region where tuberculosis highly endemic. Currently, one the recognised risk factors tuberculosis. No study has reported magnitude among patients Uganda, countries with high burden This was cross-sectional conducted 260 consenting adult confirmed diagnosis admitted on pulmonology wards Mulago national referral and teaching hospital Kampala, Uganda to determine prevalence associated clinical factors. Laboratory findings as well socio-demographic data collected using validated questionnaire obtained. Point care random blood sugar (RBS) testing performed all prior initiation anti treatment. Diabetes diagnosed if RBS level ≥ 200mg/dl presence classical symptoms mellitus. The 8.5%. Only 5 (1.9%) TB had known at enrolment. Majority participants TB-DM co-infection type 2 (n=20, 90.9%). At bivariate analysis, raised mean ALT concentrations ≥80 U/L were DM (OR-6.1, 95% CI 1.4-26.36, p=0.032) paradoxically, HIV protective (OR-0.32, 0.13-0.79, P=0.016). relationship between that remained statistically significant multivariate analysis (HIV: OR- 0.17 95%CI 0.06-0.51, p=0.002 ALT: OR-11.42 2.15-60.59, p=0.004). demonstrates common hospitalized Uganda. predictors serum alanine transaminase concentrations.