Bullous pemphigoid in a 19-year-old woman. A case with unusual target antigens.

作者: O. MORI , H. HACHISUKA , M. KUSUHARA , Y. SASAI , S. FUJIWARA

DOI: 10.1111/J.1365-2133.1994.TB02909.X

关键词:

摘要: Summary We report a 19-year-old woman with typical clinical histological and immunofluorescence features of bullous pemphigoid. By immunoblotting, the serum was shown to detect antigens at 240 138 kDa. Elevated IgK levels were present, there marked peripheral blood eosinophilia. The degree eosinophilia correlated small changes in severity skin lesions, IgE level showed correlation severity. Another unusual feature an exacerbation her disease time first menses after onset

参考文章(21)
D. F. Mutasim, G. J. Anhalt, R. S. Labib, L. A. Diaz, H. P. Patel, Molecular heterogeneity of the bullous pemphigoid antigens as detected by immunoblotting. Journal of Immunology. ,vol. 136, pp. 1231- 1235 ,(1986)
Mary Ann Robledo, Soo-Chan Kim, Neil J Korman, John R Stanley, Ramzy S Labib, Shozo Futamura, Grant J Anhalt, Studies of the Relationship of the 230-kD and 180-kD Bullous Pemphigoid Antigens Journal of Investigative Dermatology. ,vol. 94, pp. 793- 797 ,(1990) , 10.1111/1523-1747.EP12874652
C J Gibbs, I I Coutts, R Lock, O C Finnegan, R J White, Premenstrual exacerbation of asthma. Thorax. ,vol. 39, pp. 833- 836 ,(1984) , 10.1136/THX.39.11.833
John R. Stanley, Pamela Hawley-Nelson, Stuart H. Yuspa, Ethan M. Shevach, Stephen I. Katz, Characterization of bullous pemphigoid antigen: A unique basement membrane protein of stratified squamous epithelia Cell. ,vol. 24, pp. 897- 903 ,(1981) , 10.1016/0092-8674(81)90115-X
John R. Stanley, David T. Woodley, Stephen I. Katz, Identification and Partial Characterization of Pemphigoid Antigen Extracted from Normal Human Skin Journal of Investigative Dermatology. ,vol. 82, pp. 108- 111 ,(1984) , 10.1111/1523-1747.EP12259224
W. Ray Gammon, Robert A. Briggaman, Alfred O. Inman, Laurinda L. Queen, Clayton E. Wheeler, Differentiating Anti-Lamina Lucida and Anti-Sublamina Densa Anti-BMZ Antibodies by Indirect Immunofluorescence on 1.0 M Sodium Chloride-Separated Skin Journal of Investigative Dermatology. ,vol. 82, pp. 139- 144 ,(1984) , 10.1111/1523-1747.EP12259692
Philippe Bernard, Liliane Didierjean, François Denis, Jean-Hilaire Saurat, Jean-Marie Bonnetblanc, Heterogeneous bullous pemphigoid antibodies: detection and characterization by immunoblotting when absent by indirect immunofluorescence. Journal of Investigative Dermatology. ,vol. 92, pp. 171- 174 ,(1989) , 10.1111/1523-1747.EP12276689
Carl E. Arbesman, IgE Levels in Sera of Patients With Pemphigus or Bullous Pemphigoid Archives of Dermatology. ,vol. 110, pp. 378- 381 ,(1974) , 10.1001/ARCHDERM.1974.01630090016003
Lawrence L. Bushkell, Robert E. Jordon, Bullous pemphigoid: A cause of peripheral blood eosinophilia Journal of The American Academy of Dermatology. ,vol. 8, pp. 648- 651 ,(1983) , 10.1016/S0190-9622(83)70073-3
Donald F. Fincher, Bullous Pemphigoid in Childhood Archives of Dermatology. ,vol. 103, pp. 88- 90 ,(1971) , 10.1001/ARCHDERM.1971.04000130090015