Iron-based magnetic nanoparticles for magnetic resonance imaging

摘要: Abstract Magnetic resonance imaging (MRI) has been an extensive area of research owing to its depth penetration for clinical diagnosis. Signal intensity under MRI is related both T1, spin-lattice relaxation, and T2, spin-spin relaxation. To increase the contrast variability MRI, several agents are being used, i.e. T1 (e.g. gadolinium) T2 iron-based magnetic nanoparticles). These administered prior scanning visibility. They reduce relaxation times produce hyperintense hypointense signals, respectively. Tunable properties nanoparticles coating materials provide a platform get superb in weighted images. It found that enhancement by dependent on size, shape, composition, surface, which can be tuned with synthesis method material. Therefore, understanding vital contribute MR signal directing scientist design engineered nanoparticles. This paper introduces concept enhancement. We mainly discuss agents, modification these followed their biomedical applications.