Enhanced Characterization of Naproxen Formulation by Near Infrared Spectroscopy
作者： Wei Luo , Yanxin Liu , Feng Peng , Si Li , Hui Li
DOI: 10.1080/00032719.2014.903408
关键词:
摘要: Near infrared spectroscopy in combination with appropriate chemometric methods is an effective technique for quantitative analysis of parameters of interest for the pharmaceutical industry. In this study, the artificial neural network (ANN) was applied to monitor critical parameters (compression force, tablet hardness, mean particle size, and active pharmaceutical ingredient concentration of tablets) in the process of naproxen pharmaceutical preparation. The performance of ANN was compared to linear methods …
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