Use of Microdialysis in Preclinical and Clinical Development of Anticancer Agents
DOI: 10.1007/978-1-59259-734-5_19
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摘要: Major advances have been made in the use of cancer chemotherapy (1). However, most patients, especially those diagnosed with solid tumors, fail to respond initial treatment or relapse after an response Thus, there is a need identify factors associated lack and develop new strategies that address factors. The development effective chemotherapeutic agents for tumors depends, part, on ability achieve cytotoxic drug concentrations exposure within tumor (2,3).
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S. Baunach, Jürgen Meixensberger, M. Gerlach, J. Lan, K. Roosen, Intraoperative microdialysis and tissue-pO2 measurement in human glioma. Acta Neurochirurgica. ,vol. 71, pp. 241- 243 ,(1998) , 10.1007/978-3-7091-6475-4_69
J F Thompson, G A Siebert, Y G Anissimov, B M Smithers, A Doubrovsky, C D Anderson, M S Roberts, Microdialysis and response during regional chemotherapy by isolated limb infusion of melphalan for limb malignancies British Journal of Cancer. ,vol. 85, pp. 157- 165 ,(2001) , 10.1054/BJOC.2001.1902
Harris Busch, Vincent T. DeVita, Cancer drug development Academic Press. ,(1979)
Ronald G. Blasberg, Kevin P. Claffey, Juri G. Tjuvajev, Tadashi Miyagawa, Ronald Finn, Revathi Joshi, Arjun Joshi, Takamitsu Oku, Toshio Sasajima, Tumor Growth Modulation by Sense and Antisense Vascular Endothelial Growth Factor Gene Expression: Effects on Angiogenesis, Vascular Permeability, Blood Volume, Blood Flow, Fluorodeoxyglucose Uptake, and Proliferation of Human Melanoma Intracerebral Xenografts Cancer Research. ,vol. 58, pp. 4185- 4192 ,(1998)
K J Harrington, G Rowlinson-Busza, K N Syrigos, P S Uster, R M Abra, J S W Stewart, Biodistribution and pharmacokinetics of 111In-DTPA-labelled pegylated liposomes in a human tumour xenograft model: implications for novel targeting strategies. British Journal of Cancer. ,vol. 83, pp. 232- 238 ,(2000) , 10.1054/BJOC.1999.1232
Mary J. Johansen, Timothy Madden, Robert A. Newman, The use of microdialysis in pharmacokinetics and pharmacodynamics. Pharmacotherapy. ,vol. 17, pp. 464- 481 ,(1997) , 10.1002/J.1875-9114.1997.TB03057.X
Steven A. Rosenberg, Vincent T. DeVita, Samuel Hellman, Cancer : Principles and Practice of Oncology ,(1982)
Richard L. Heideman, Mary K. Danks, William C. Zamboni, Timothy D. Mandrell, Clinton F. Stewart, Stephanie L. Einhaus, Amar J. Gajjar, William P. Rogers, Peter J. Houghton, A four-hour topotecan infusion achieves cytotoxic exposure throughout the neuraxis in the nonhuman primate model: implications for treatment of children with metastatic medulloblastoma. Clinical Cancer Research. ,vol. 4, pp. 2537- 2544 ,(1998)
Andrew S. Janoff, Liposomes: Rational Design ,(1998)
Natalie A. Wisniewski, Bruce Klitzman, Christiane C. Poellmann, Amanda A. Gaskin, Mark W. Dewhirst, Jean M. Poulson, Jennifer S. Shoemaker, Susan N. Ettinger, Urea as a Recovery Marker for Quantitative Assessment of Tumor Interstitial Solutes with Microdialysis Cancer Research. ,vol. 61, pp. 7964- 7970 ,(2001)