Cardiac surgery for children with trisomies 13 and 18: Where are we now?

摘要: The objective is to examine whether cardiac surgery should be considered for children with trisomy 13 or 18 (T13 18).T13 were previously referred as "lethal" conditions due high mortality rates and severe disability among survivors. In the last decade, investigations have revealed these are heterogeneous, increasing numbers of studies describing interventions children. A number factors makes interpretation reported outcomes after challenging: (1) dissimilarities in practice lead a wide variation surgery; (2) generally offered older, healthier children; (3) surgeries widely varying risks often lumped together individual studies, (4) cases where has been withheld not included publications. It unclear withholding some ventricular septal defect will death, development pulmonary hypertension, if death occur from other causes. this article, we describe two different clinical situations would benefit them how communicate their families. Cardiac may beneficial 18, but harm others. Every child approached an fashion goals each family addressed. Children who more likely without respiratory support. Rigorous transparent research needed identify that affect survival 18.