Control of the Initiation of Lambda Replication, oop, lit and Repressor Establishment RNA Synthesis

作者: Sidney Hayes

DOI: 10.1007/978-1-4684-0844-7_11

关键词:

摘要: A goal of our work is to understand the mechanism for initiation replication and stimulation transcription from origin (ori) region bacteriophage lambda. The λ bidirectional DNA synthesis two modes transcription, (a) oop, lit RNA (b) repressor establishment are regulated by ori dependent events. requirements summarized in this report. Transcription measured noninduced induced prophage which derepressed thermally inactivating repressor. This system provides highly reproducible synchrony permits characterization development initially one phage per cell.

参考文章(53)
Julian D. Gross, DNA Replication in Bacteria With 6 Figures Current Topics in Microbiology and Immunology. ,vol. 57, pp. 39- 74 ,(1972) , 10.1007/978-3-642-65297-4_2
G R Smith, J Hedgpeth, Oligo(A) not coded by DNA generating 3'-terminal heterogeneity in a lambda phage RNA. Journal of Biological Chemistry. ,vol. 250, pp. 4818- 4821 ,(1975) , 10.1016/S0021-9258(19)41377-X
Ian J. Molineux, Susan Friedman, Malcolm L. Gefter, Purification and Properties of the Escherichia coli Deoxyribonucleic Acid-unwinding Protein Journal of Biological Chemistry. ,vol. 249, pp. 6090- 6098 ,(1974) , 10.1016/S0021-9258(19)42224-2
G. Scherer, G. Hobom, H. Kössel, DNA base sequence of the po promoter region of phage lamdba. Nature. ,vol. 265, pp. 117- 121 ,(1977) , 10.1038/265117A0
Alfred Day Hershey, The Bacteriophage Lambda. ,(1971)
Y Takeda, A Folkmanis, H Echols, Cro regulatory protein specified by bacteriophage lambda. Structure, DNA-binding, and repression of RNA synthesis. Journal of Biological Chemistry. ,vol. 252, pp. 6177- 6183 ,(1977) , 10.1016/S0021-9258(17)40047-0
Tomoko Ogawa, Jun-ichi Tomizawa, Replication of bacteriophage DNA: I. Replication of DNA of lambda phage defective in early functions☆ Journal of Molecular Biology. ,vol. 38, pp. 217- 225 ,(1968) , 10.1016/0022-2836(68)90407-5
Haruo Saito, Hisao Uchida, Initiation of the DNA replication of bacteriophage lambda in Escherichia coli K12. Journal of Molecular Biology. ,vol. 113, pp. 1- 25 ,(1977) , 10.1016/0022-2836(77)90038-9
A. Honigman, S.-L. Hu, R. Chase, W. Szybalski, 4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage λ Nature. ,vol. 262, pp. 112- 116 ,(1976) , 10.1038/262112A0
Anne Joyner, L.N. Isaacs, H. Echols, W.S. Sly, DNA replication and messenger RNA production after induction of wild-type λ bacteriophage and λ mutants Journal of Molecular Biology. ,vol. 19, pp. 174- 186 ,(1966) , 10.1016/S0022-2836(66)80059-1