Forsythoside A protects against lipopolysaccharide-induced acute lung injury through up-regulating microRNA-124
作者： Zibin Lu , Huayi Yang , Huihui Cao , Chuying Huo , Yuyao Chen
DOI: 10.1042/CS20200598
关键词:
摘要: Acute lung injury (ALI) is a life-threatening disease without effective pharmacotherapies, so far. Forsythia suspensa is frequently used in the treatment of lung infection in traditional Chinese medicine. In search for natural anti-inflammatory components, the activity and the underlying mechanism of Forsythoside A (FA) from Forsythia suspensa were explored. In the present paper, BALB/c mice and murine RAW 264.7 cells were stimulated by LPS to establish inflammation models. Data showed that FA inhibited the production of TNF-α and …
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