Three-Dimensional Measurement of Hepatocellular Carcinoma Ablation Zones and Margins for Predicting Local Tumor Progression.

摘要: Abstract Purpose To propose a postprocessing technique that measures tumor surface with insufficient ablative margins (≤ 5 mm) on magnetic resonance (MR) imaging to predict local progression (LTP) following radiofrequency (RF) ablation. Materials and Methods A diagnostic method is proposed based measurement of margin ≤ mm MR imaging. The includes fully automatic registration pre- post–RF ablation imaging, semiautomatic segmentation pre–RF volume, subsequent calculation the three-dimensional exposed area. ability use this recurrence at 2 years was then tested 16 patients cirrhosis who were treated by RF in 2012: eight LTP matched according size number α-fetoprotein level versus without recurrence. Results error estimated less than 12%. log-rank test showed area > 425 had 2-year rate 77.5%, compared 25% for (P = .018). Conclusions This proof-of-concept study proposes an accurate reliable estimate margins, underscores potential usefulness stratify HCC their risk LTP.