Breast Cancer Stem Cells

摘要: Cancer of the breast is most common tumor in women Western-world countries. The expressions luminal markers as ERα and GATA3 tumors suggest that their origin normal cells. Analogously, expression CK5 CK17 basal like may a source from myoepithelial/basal compartment. However this logic not explained progenitors are target population for development basal-tumors. This finding supports idea features necessarily reflect cell origin. In sense it would be possible cancer stem cells (BCSCs) could play an important role cancer. Stem Cells Hypothesis has become more widely accepted. existence CSC consequences prevention therapy. Preventive strategies focused reducing number CSCs mean to reduce risk topic high concern. technological advances identification have favoured better understanding mechanisms involved metastasis late relapse