A Novel and Efficient Method for the Preparation of Asymmetric Dithioacetals.

摘要: Abstract Aldehydes and ketones react with one equivalent each of thiols thiolacetic acid under catalysis to yield almost exclusively the mixed alkylthio-(or arylthio-) acylthioacetals. Reaction thioacetal a nucleophile (such as NaOMe) liberates thiolate anion which can be trapped variety electrophiles provide asymmetric dithioacetals in high yields.