Increased Vulnerability to Oxidative Stress and Mitochondrial Dysfunction in Autism
作者： Abha Chauhan , Ved Chauhan
DOI: 10.1007/978-1-4939-2190-4_20
关键词:
摘要: The exact cause of autism is not known but the role genetic and environmental factors as well oxidative stress have been suggested in autism. Accumulating evidence also suggests defects mitochondrial electron transport chain complexes individuals with autism, which may lead to abnormal energy metabolism increased stress. Several studies reported damage evident by lipid peroxidation, protein DNA oxidation decreased antioxidant status (enzymatic non-enzymatic) indicated glutathione—redox imbalance activities enzymes blood, urine brain tissues subjects Here, we review stress, dysfunction variations that can increase vulnerability
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