Repeated cross-fostering affects maternal behavior and olfactory preferences in rat pups.

摘要: Disturbances in early mother-infant relationships are strongly associated with changes the development of a number physiological and behavioral systems neonate that can create complex change patterns vulnerability throughout life. Institutionalized children, despite receiving adequate care, display important adult life, such lack selective consistent attachment to maternal figure It is not yet clear how human adoption processes alter relationship Here, mimic situation explore impact on formation between infant caregiver, we use repeated cross-fostering (RCF) model rodents two postnatal periods, days (PND) 1 3 (early RCF) 9 11 (late RCF). Early exposure but late RCF reduces pups' preference for odor mother figure. Moreover, slightly later reduce care motivation collecting pups bringing them nest. The protocol creates an unstable environment mother-pup interaction, it seems affect learned only when occurs during corresponding sensitive period development.