CXCR4 pathway associated with family history of melanoma

作者: Wen-Qing Li , Jiali Han , Hans R. Widlund , Mick Correll , Yaoyu E. Wang

DOI: 10.1007/S10552-013-0315-9

关键词:

摘要: Purpose Genetic predisposition plays a major role in the etiology of melanoma, but known genetic markers only account for limited fraction family-history-associated melanoma cases. Expression microarrays have offered opportunity to identify further genomic profiles correlated with family history melanoma. We aimed distinguish mRNA expression signatures between cases and without

参考文章(40)
Robert Gentleman, Vincent J Carey, Wolfgang Huber, Rafael A Irizarry, Sandrine Dudoit, Bioinformatics and Computational Biology Solutions Using R and Bioconductor ,(2006)
G. K. Smyth, limma: Linear Models for Microarray Data Springer, New York, NY. pp. 397- 420 ,(2005) , 10.1007/0-387-29362-0_23
David J. Sieg, Christof R. Hauck, Dusko Ilic, Candice K. Klingbeil, Erik Schaefer, Caroline H. Damsky, David D. Schlaepfer, FAK integrates growth-factor and integrin signals to promote cell migration Nature Cell Biology. ,vol. 2, pp. 249- 256 ,(2000) , 10.1038/35010517
D Anderson, C. Koch, L Grey, C Ellis, M. Moran, T Pawson, Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors Science. ,vol. 250, pp. 979- 982 ,(1990) , 10.1126/SCIENCE.2173144
Cristina Delgado-Martín, Cristina Escribano, José Luis Pablos, Lorena Riol-Blanco, José Luis Rodríguez-Fernández, Chemokine CXCL12 Uses CXCR4 and a Signaling Core Formed by Bifunctional Akt, Extracellular Signal-regulated Kinase (ERK)1/2, and Mammalian Target of Rapamycin Complex 1 (mTORC1) Proteins to Control Chemotaxis and Survival Simultaneously in Mature Dendritic Cells Journal of Biological Chemistry. ,vol. 286, pp. 37222- 37236 ,(2011) , 10.1074/JBC.M111.294116
Elda Righi, Satoshi Kashiwagi, Jianping Yuan, Michael Santosuosso, Pierre Leblanc, Rachel Ingraham, Benjamin Forbes, Beth Edelblute, Brian Collette, Deyin Xing, Magdalena Kowalski, Maria Cristina Mingari, Fabrizio Vianello, Michael Birrer, Sandra Orsulic, Glenn Dranoff, Mark C. Poznansky, CXCL12/CXCR4 Blockade Induces Multimodal Antitumor Effects That Prolong Survival in an Immunocompetent Mouse Model of Ovarian Cancer Cancer Research. ,vol. 71, pp. 5522- 5534 ,(2011) , 10.1158/0008-5472.CAN-10-3143
Minah Kim, Young Jun Koh, Kyung Eun Kim, Bong Ihn Koh, Do-Hyun Nam, Kari Alitalo, Injune Kim, Gou Young Koh, CXCR4 Signaling Regulates Metastasis of Chemoresistant Melanoma Cells by a Lymphatic Metastatic Niche Cancer Research. ,vol. 70, pp. 10411- 10421 ,(2010) , 10.1158/0008-5472.CAN-10-2591
Teri A Manolio, Francis S Collins, Nancy J Cox, David B Goldstein, Lucia A Hindorff, David J Hunter, Mark I McCarthy, Erin M Ramos, Lon R Cardon, Aravinda Chakravarti, Judy H Cho, Alan E Guttmacher, Augustine Kong, Leonid Kruglyak, Elaine Mardis, Charles N Rotimi, Montgomery Slatkin, David Valle, Alice S Whittemore, Michael Boehnke, Andrew G Clark, Evan E Eichler, Greg Gibson, Jonathan L Haines, Trudy FC Mackay, Steven A McCarroll, Peter M Visscher, None, Finding the missing heritability of complex diseases. Nature. ,vol. 461, pp. 747- 753 ,(2009) , 10.1038/NATURE08494
Edneia A. S. Ramos, Mariana Grochoski, Karin Braun-Prado, Gerusa G. Seniski, Iglenir J. Cavalli, Enilze M. S. F. Ribeiro, Anamaria A. Camargo, Fabrício F. Costa, Giseli Klassen, Epigenetic Changes of CXCR4 and Its Ligand CXCL12 as Prognostic Factors for Sporadic Breast Cancer PLoS ONE. ,vol. 6, pp. e29461- ,(2011) , 10.1371/JOURNAL.PONE.0029461
Fran Balkwill, Cancer and the chemokine network Nature Reviews Cancer. ,vol. 4, pp. 540- 550 ,(2004) , 10.1038/NRC1388