A simple synthesis of 2-keto-3-deoxy-D-erythro-hexonic acid isopropyl ester, a key sugar for the bacterial population living under metallic stress.
作者： Claire M. Grison , Brice-Loïc Renard , Claude Grison
DOI: 10.1016/J.BIOORG.2013.11.006
关键词:
摘要: 2-Keto-3-deoxy-D-erythro-hexonic acid (KDG) is the key intermediate metabolite of Entner Doudoroff (ED) pathway. A simple, efficient and stereoselective synthesis KDG isopropyl ester described in five steps from 2,3-O-isopropylidene-D-threitol with an overall yield 47%. studied as attractive marker a functional used to promote growth ammonium producing bacterial strains, showing interesting features remediation heavy-metal polluted soils.
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