The Thymoma and Thymic Hyperplasia in Myasthenia Gravis with Observations on the General Pathology

摘要: Since the comprehensive study by Bell in 1917 no systematic treatise on thymic tumors of myasthenia gravis has appeared. It might be expected that past twenty years would have added records many more cases to literature and extended our knowledge pathological anatomy associated tumors. On contrary but few with autopsy findings been reported conceptions concerning morbid this disease are much same as they were 1917. In period from 1901, year which Weigert published record first case an thymus tumor, 1917, found reports 56 autopsied disease. He wrote: “The was described enlarged seventeen these cases; ten others it contained a tumor. Therefore some form involvement seems occur nearly half gravis.” 6 autopsies 5 showed lesions. Of 4 here, 2 had lesions recognized. I am opinion pathologic changes may direct ratio care sought. Thus, prior when called attention association, presence completely overlooked. 1912 Starr reviewed 250 gravis, including 1901 probably not carefully investigated. His figures only 28 per cent cases, while Bell9s analysis between yielded incidence 50 cent. With addition elsewhere since remains at This figure expresses frequency grossly recognizable thymus. quite possible, however, produced little or macroscopic alteration suprapericardial tissue overlooked cases. place, will pointed out later on, lesion without microscopic examination. second place region post-adolescent ages is frequently passed over routine necropsy most cursory inspection. These facts doubtless combined lower