Polypharmacy in patients with schizophrenia.

摘要: Background: Polypharmacy in patients with schizophrenia is a common practice little basis well-controlled studies. The objective of this report to describe the changes prescription practices psychotropic medications for diagnosed 1995 and 2000. Method: medical records who were discharged from our facility 2000 diagnosis (DSM-IV criteria) reviewed. at discharge compared. incidence adverse drug reactions indicators patient outcome also Results: 459 reviewed 584 Patients significantly more likely receive antidepressants, mood stabilizers, anxiolytics, multiple antipsychotics than (p <.0001). given fewer anticholinergics There was large increase use divalproex. No on treatment 1 antipsychotic 1995, whereas 2000, 15.9% were. most combination haloperidol olanzapine. Paralleling increased polypharmacy, there =.002). In addition, had shorter lengths stay <.0001) be community state hospital =.0001). Conclusion: This study found that acutely ill hospitalized are being treated medications, including I antipsychotic. These coincidental decrease an improvement outcome.