Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
作者： Mark Whitaker , Trevor Charles Roche , Zhong Jiang , Osama Ahmed Aswania
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摘要: A drug product comprising: a dry powder inhalation device containing one or more pharmaceutical compositions present therein, wherein the comprise active ingredients (I) 4-{(1R)-2-[(6-{2-[(2,6- dichlorobenzyl)oxy]ethoxy} hexyl)amino]-1-hydroxyethyl}-2- (hydroxymethyl)phenol, salt thereof, and (II) (6α,11s,16α,17α)-6,9-difluoro- 17-{[(fluoromethyl)thio]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien- 7-yl 2- furancarboxylate solvate thereof; hygroscopic material; package which encompasses material defining an enclosed volume therein; each of are in same different compositions, within exhibits Relative Humidity from 20% to 40%.
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