The bioassay of thyrotropin in serum.

摘要: A bioassay technique for thyrotropin in serum was developed from that of Adams and Purves. Mice were injected with I131 then had endogenous suppressed by the administration thyroxine followed thyroid powder. The effect an intravenous injection or test sub-stance measured percentage increase blood I131. This a linear relationship to logarithm dose. Sensitivity 0.025 mu., injec-tion volume 0.5 ml., average index precision (λ) 0.24 achieved With this sera 6 patients myxedema measured. Endogenous thyrotropic activity shown travel on electrophoresis gamma globulin such also present only fraction (II) Cohn fractions human plasma.