Convolvulus galaticus, Crocus antalyensis, and Lilium candidum extracts show their antitumor activity through induction of p53-mediated apoptosis on human breast cancer cell line MCF-7 cells.

作者: Onur Tokgun , Hakan Akca , Ramazan Mammadov , Candan Aykurt , Gökhan Deniz

DOI: 10.1089/JMF.2012.0050

关键词:

摘要: Abstract Conventional and newly emerging treatment procedures such as chemotherapy, catalytic therapy, photodynamic radiotherapy have not succeeded in reversing the outcome of cancer diseases to any drastic extent, which has led researchers investigate alternative options. The extensive repertoire traditional medicinal knowledge systems from various parts world are being re-investigated for their healing properties. It been reported that several members Convolvulaceae, Iridaceae, Liliaceae families antitumor activity against some tumor cell lines. Here we first report Convolvulus galaticus, Crocus antalyensis, Lilium candidum species cytotoxic on human breast line MCF-7 cells. Plant samples were collected identified, effects examined at different concentrations methanol extracts. We found all three plants cells but C. ga...

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