Diffusion-Weighted Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features of Abdominal Viscera in a Patient with Gaucher's Disease.

作者: Ramazan Kutlu , Alpay Alkan , Aysegül Kahraman , Gulnur Erdem , Tugce Ozlem Kalayci

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摘要: A 46-year-old woman with Gaucher’s disease (GD) consulted our clinic for abdominopelvic magnetic resonance imaging (MRI), as physical examination had revealed hepatosplenomegaly. Upper abdominal MRI showed massive hepatosplenomegaly and innumerable hypointense splenic nodules on T1-weighted images. Diffusion-weighted (DW-MRI) spectroscopy (MRS) were performed to liver parenchyma nodules. MRS lactate, lipid, acetate, alanine peaks in nodules, choline, creatine, myo-inositol-glycine, lactate the parenchyma. The DW-MRI diffusion restriction It was concluded that is a reliable method diagnosis follow up of GD. Coupling allows quantitative evaluation, thereby increasing efficacy method. This first report literature presenting advanced findings

参考文章(9)
Ozgür Kiliçkesmez, Sibel Bayramoğlu, Gülseren Yirik, Tan Cimilli, Sibel Aydin, Non-breath-hold high b-value diffusion-weighted MRI with parallel imaging technique: apparent diffusion coefficient determination in normal abdominal organs. Diagnostic and Interventional Radiology. ,vol. 14, pp. 83- 87 ,(2008)
S C Hill, B M Damaska, A Ling, K Patterson, A M Di Bisceglie, R O Brady, N W Barton, Gaucher disease: abdominal MR imaging findings in 46 patients. Radiology. ,vol. 184, pp. 561- 566 ,(1992) , 10.1148/RADIOLOGY.184.2.1620865
Dow-Mu Koh, David J. Collins, Diffusion-weighted MRI in the body: applications and challenges in oncology. American Journal of Roentgenology. ,vol. 188, pp. 1622- 1635 ,(2007) , 10.2214/AJR.06.1403
F. Fischbach, T. Schirmer, M. Thormann, T. Freund, J. Ricke, H. Bruhn, Quantitative proton magnetic resonance spectroscopy of the normal liver and malignant hepatic lesions at 3.0 Tesla European Radiology. ,vol. 18, pp. 2549- 2558 ,(2008) , 10.1007/S00330-008-1040-8
Shigeo Takebayashi, Shinichirho Iso, Yasuhiko Nagano, Chikara Kunisaki, Ayumi Murakami, Takeshi Sasaki, CT findings of Gaucher disease with large, calcified splenic masses mimicking tumors European Journal of Radiology Extra. ,vol. 69, pp. e65- e68 ,(2009) , 10.1016/J.EJREX.2008.07.008
Ahmed Abdel Khalek Abdel Razek, Ahmed Abdalla, Abeer Fathy, Ahmed Megahed, Apparent diffusion coefficient of the vertebral bone marrow in children with Gaucher's disease type I and III. Skeletal Radiology. ,vol. 42, pp. 283- 287 ,(2013) , 10.1007/S00256-012-1464-8
Ahmed Abdel Khalek Abdel Razek, Ahmed Abdalla, Nahed Abdel Gaber, Abeer Fathy, Ahmed Megahed, Tarek Barakat, Mona Abdel latif Alsayed, Proton MR Spectroscopy of the brain in children with neuronopathic Gaucher’s disease European Radiology. ,vol. 23, pp. 3005- 3011 ,(2013) , 10.1007/S00330-013-2924-9
Ahmed Abdel Khalek Abdel Razek, Nahed Abd El-Gaber, Ahmed Abdalla, Abeer Fathy, Ahmed Azab, Ashraf Abdel Rahman, Apparent diffusion coefficient vale of the brain in patients with Gaucher’s disease type II and type III Neuroradiology. ,vol. 51, pp. 773- 779 ,(2009) , 10.1007/S00234-009-0548-1
M R Terk, J Esplin, K Lee, G Magre, P M Colletti, MR imaging of patients with type 1 Gaucher's disease: relationship between bone and visceral changes. American Journal of Roentgenology. ,vol. 165, pp. 599- 604 ,(1995) , 10.2214/AJR.165.3.7645477