Are changes in intracranial pressure during intermittent machine haemofiltration dependent upon membrane biocompatibility

作者: A. Davenport , A.M. Davison , E.J. Will

DOI: 10.1177/039139888901201107

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摘要: We measured the intracranial pressure, using a subdural catheter in three patients admitted with grade 4 hepatic encephalopathy following paracetamol (aminocetaphen) self poisoning. Acute oliguric renal failure was present all cases and treated daily intermittent machine haemofiltration. Hypovolaemia prior to treatment corrected total of 14 isovolaemic 17 litre exchanges carried out either Gambro FH77 (8) or Hospal 3600 (6) haemofilter. Intracranial pressure (ICP) increased during both types filter, but increase greater group, mean ICP from 7.6 +/- 2 mmHg 12 3 at hours (p less than 0.05), this associated fall percentage change pretreatment value arterial oxygen tension peripheral white blood cell count first hour compared 8 2% vs 1 0.05) 5 0.05). This suggests that membrane biocompatibility may also play role development

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