Therapeutic activities of PHA-L4, the mitogenic isolectin of phytohemagglutinin.

摘要: Evidence is presented that suggests PHA-L4 may exert the therapeutic effects of a theoretical ideal biological response modifier through its ability to do following: assist remission induction in certain malignancies, exhibit direct antitumor cytotoxic effects, enhance antineoplastic effect radiation and chemotherapy, decrease liability malignant transformation, promote differentiation restore normal growth responses neoplastic cells, manifest minimal suppressor activity would inhibit tumor rejection or cytotoxicity, repress graft graft-versus-host amplify immunosuppressive other agents allograft transplantations, display protective against damage from stimulate myelopoiesis, reinforce various infections, immunogenicity, attract mononuclear cells sites injection local application.146 references.