作者: Maike Keck , David Benjamin Lumenta , Lars-Peter Kamolz
DOI: 10.1007/978-3-7091-1586-2_2
关键词:
摘要: The skin is the largest organ in body making up 16 % of weight, with a surface area 1.8 m2. Because it interfaces environment, primarily serves as protective barrier allowing and limiting inward outward passage water, electrolytes various substances while providing protection against microorganisms, ultraviolet radiation, toxic agents mechanical insults. An injury large portions skin, severely burned patients, may result significant disability or even death. Limitations use autografts local free flaps patients soft tissue loss have lead to development tissue-engineered skin. term engineering came 1987 combining knowledge from field biology create bioartificial for regenerative medicine.