Kinetic Isotope Effect Characterization of the Transition State for Oxidized Nicotinamide Adenine Dinucleotide Hydrolysis by Pertussis Toxin

作者: Johannes Scheuring , Vern L. Schramm

DOI: 10.1021/BI962841H

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摘要: Pertussis toxin from Bordatella pertussis catalyzes the ADP ribosylation of several G-proteins, using NAD+ as a substrate. In absence an acceptor protein, acts glycohydro...

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