Analogies and disparities among scintigraphic bone tracers in the diagnosis of cardiac and non-cardiac ATTR amyloidosis.

摘要: In this issue of JNC, BW Spery and Coll report a retrospective analysis 57 patients with transthyretin-related amyloidosis (ATTR) in an advanced phase the disease who underwent 99mTechnetium-pyrophosphate (99mTcPYP) scintigraphy. Although relatively small “negative,” study is relevant since it broadens our knowledge on uptake “bone tracers” ATTR contributes to understand limitations clinical use scintigraphy disease. The paper raises, directly or indirectly, at least three questions: To what extent are different bone tracers interchangeable for diagnosis cardiac amyloidosis? Are able image non-cardiac What explanation variable performance extracardiac