Synthesis of Water-Soluble, Ester-Terminated Dendrons and Dendrimers Containing Internal PEG Linkages

摘要: Dendrimers up to three generations, possessing internal PEG units within the branching framework, were synthesized by a convergent approach via reaction of amine-based dendrons 6, 9, and 11 with 6,6-bis(4-chlorocarbonyl-2-oxabutyl)-4,8-dioxaundecane-1,11-dicarbonyl chloride. These new constructs fully characterized, shown exhibit good solubilities in organic as well aqueous solvents, demonstrated solubilize lithium triflate salts nonaqueous environments, such chloroform.