摘要: The development of pulmonary fibrosis is the end point a wide range respiratory diseases including organic and inorganic dust exposure, infection, acute lung injury, radiation, idiopathic interstitial pneumonias (IIP), connective tissue diseases. most common fibrotic disorder (IPF), an IIP with histological appearance usual pneumonia (UIP). Formerly also known as cryptogenic fibrosing alveolitis (CFA), definition this disease has evolved in recent years to exclude non-specific (NSIP), sub-type more diffuse fibrosis, different clinical course better prognosis than IPF. This change must be considered when looking at historical studies that grouped UIP NSIP under same umbrella term.