The penetration of 14C-urea and 3H-water into the rat brain with cold-induced cerebral oedema. Histological and autoradiographic study of the oedema. The effect of urovert.
作者： K. G. Go , F. van Woudenberg , M. G. Woldring , E. J. Ebels , J. W. F. Beks
DOI: 10.1007/BF01540919
关键词:
摘要: In albino rats a left-sided cortical cold injury was studied histologically and by131I-RISA-autoradiography. The penetration of14C-urea and3H-water into brain skeletal muscle determined at various time intervals after intravenous injection of the markers, given in saline one experimental series, urovert another series. There 4% increase water content cortex white matter on side lesion. The14C-urea uptake by uninjured tissue showed demonstrable blood-brain barrier effect; injured it characterized breakdown barrier. impaired function also apparent from leakage exudate lesion, spreading underlying as shown RISA-autoradiography. The3H-water not impeded any delayed3H-water suggested decreased local blood flow. effect mainly dilution plasma radioactivity; dehydration tissues demonstrated.
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sci-hub.se 参考文章(52)
Abel Lajtha, Givlio Levi, Ronald Blasberg, Specificity of Cerebral Amino Acid Transport Springer, Vienna. pp. 367- 381 ,(1967) , 10.1007/978-3-7091-7545-3_27
ter Weeme Ca, Ebels Ej, Beks Jw, Go Kg, The spreading of cerebral edema from a cold injury in cats. Psychiatria, neurologia, neurochirurgia. ,vol. 70, pp. 403- ,(1967)
Raymond A. Clasen, Howard H. Sky-Peck, Sylvia Pandolfi, Iris Laing, George M. Hass, The Chemistry of Isolated Edema Fluid in Experimental Cerebral Injury Springer, Vienna. pp. 536- 553 ,(1967) , 10.1007/978-3-7091-7545-3_39
H. M. Zimmerman, Robert D. Terry, Richard M. Torack, The fine structure of cerebral fluid accumulation. I. Swelling secondary to cold injury. American Journal of Pathology. ,vol. 35, pp. 1135- 1147 ,(1959)
Milton W. Brightman, The intracerebral movement of proteins injected into blood and cerebrospinal fluid of mice. Progress in Brain Research. ,vol. 29, pp. 19- 40 ,(1968) , 10.1016/S0079-6123(08)64147-3
J. W. F. Beks, C. A. ter Weeme, E. J. Ebels, Alterations in the Intraventricular Pressure in Cats After Cold Induced Edema Springer, Vienna. pp. 564- 568 ,(1967) , 10.1007/978-3-7091-7545-3_41
Abel Lajtha, Jenö Toth, THE BRAIN BARRIER SYSTEM?III. Journal of Neurochemistry. ,vol. 9, pp. 199- 212 ,(1962) , 10.1111/J.1471-4159.1962.TB11861.X
J. W. F. Beks, A. Groen, T. Huizinga, K. H. N. Noordhoek, J. M. Smit, W. G. Walter, Effects of intravenously administered hypertonic urea solution Acta Neurochirurgica. ,vol. 13, pp. 1- 10 ,(1965) , 10.1007/BF02074641
JOSEPH C. LEE, Ultrastructural changes in the edematous central nervous system. II. Cold-induced edema. JAMA Neurology. ,vol. 14, pp. 36- 49 ,(1966) , 10.1001/ARCHNEUR.1966.00470070040005
Burton C. Einspruch, Kemp Clark, FURTHER STUDIES ON THE EFFECTIVENESS OF AGENTS USED TO LOWER INTRACRANIAL PRESSURE. Journal of Neurosurgery. ,vol. 23, pp. 45- 48 ,(1965) , 10.3171/JNS.1965.23.1.0045