DIALIGN-T: an improved algorithm for segment-based multiple sequence alignment.
作者： Amarendran R Subramanian , Jan Weyer-Menkhoff , Michael Kaufmann , Burkhard Morgenstern
关键词:
摘要: Background We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains number improvements compared previous version 2.2 DIALIGN. This is superior Needleman-Wunsch-based multi-alignment programs on locally related sequence sets. However, it often outperformed by these methods data sets with global but weak similarity at primary-sequence level.
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