Enzyme inhibitors of microbial origin

作者: Hamao Umezawa

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摘要: Publisher Summary This chapter explains the enzyme inhibitors of microbial origin. The study antibiotics, finds new compounds with interesting activities, studying their chemistry, biosynthesis and, mechanism action. It has been proved that a characteristic part an antibiotic is controlled by genetic material on plasmid, is, in DNA different from cell genome. ability microorganisms to produce secondary metabolites various structures due great variety plasmids. Based this microorganisms, and for purpose exploiting research area, screening initiated found culture filtrates. are useful analysis biological functions disease processes have potential utility treatment diseases. Compared macromolecular nature obtained animal plant tissues, filtrates small molecular compounds, rapidly elucidate structure activity relationships metabolism.

参考文章(11)
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